AWS HPC Blog

Category: Compute

Optimize Nextflow Workflows on AWS Batch with Mountpoint for Amazon S3

Are you running genomic workflows with Nextflow on AWS Batch and experiencing bottlenecks when staging large reference files? In this post, we will show you how to optimize your workflow performance by leveraging Mountpoint for Amazon S3 to stream reference data directly into your Nextflow processes, eliminating the need to stage large static files repeatedly.

How Rivian modernized engineering simulation using AWS

This post references AWS ParallelCluster. Check out AWS Parallel Computing Service (AWS PCS), our new managed Slurm service for running HPC and AI workloads on AWS. This post was contributed by Ameya Kamerkar (Rivian), Vikram Pendyam (Rivian), Abhishek Chauhan (Rivian), Ajay Paknikar (AWS), Sandeep Sovani (AWS) Figure 1. Rivian’s custom Amazon Electric Delivery Vehicle (EDV) […]

Running NVIDIA Cosmos world foundation models on AWS

Running NVIDIA Cosmos world foundation models on AWS provides powerful physical AI capabilities at scale. This blog covers two production-ready architectures, each optimized for different organizational needs and constraints.

How Daiichi Sankyo modernized drug discovery using AWS Parallel Computing Service

This blog was co-authored by Takehiro Nakajima and Mark Azadpour from AWS and Rintaro Yamada, Rei Kajitani and Ryo Kunimoto from Daiichi Sankyo In recent years, the informatics field of drug discovery has seen a rapid increase in workloads requiring large-scale parallel computing, such as genome analysis, structure prediction, and drug design. Daiichi Sankyo has […]

AWS at SC25 - Meet the Advanced Computing team at Booth #2207

Meet the Advanced Computing team of AWS at SC25 in St. Louis

This post references AWS ParallelCluster. Check out AWS Parallel Computing Service (AWS PCS), our new managed Slurm service for running HPC and AI workloads on AWS. We want to empower every scientist and engineer to solve hard problems by giving them access to the compute and analytical tools they need, when they need them. Cloud […]

AWS re:Invent 2025: Your Complete Guide to High Performance Computing Sessions

This post references AWS ParallelCluster. Check out AWS Parallel Computing Service (AWS PCS), our new managed Slurm service for running HPC and AI workloads on AWS. AWS re:Invent 2025 returns to Las Vegas, Nevada on December 1, uniting AWS builders, customers, partners, and IT professionals from across the globe. This year’s event offers you exclusive […]

What’s the difference between AWS ParallelCluster and AWS Parallel Computing Service?

This post references AWS ParallelCluster. Check out AWS Parallel Computing Service (AWS PCS), our new managed Slurm service for running HPC and AI workloads on AWS. It’s been a year since we announced AWS Parallel Computing Service (PCS). In a way this is the third generation of Slurm-based HPC orchestrators that we’ve brought to you. […]

How DTN accelerates operational weather prediction using NVIDIA Earth-2 on AWS

Cyclone chasing just got a whole lot smarter! Check out how DTN’s AI-powered weather model is rewriting the forecast. Brace yourself for the future of weather prediction.