The DRAGEN Complete Suite enables ultra-rapid analysis of Next Generation Sequencing (NGS) data for large data sets, such as whole genomes, exomes, and genes/panels.

This dataset contains alignment files and short nucleotide, copy number (CNV), repeat expansion (STR), structural variant (SV) and other variant call files from the 1000 Genomes Project Phase 3 dataset (n=3202) using Illumina DRAGEN v3.5.7b, v3.7.6, v4.0.3, and v4.2.7 software. All DRAGEN analyses were performed in the cloud using the Illumina Connected Analytics bioinformatics platform powered by Amazon Web Services (see 'Data solution empowering population genomics' for more information). The v3.7.6 and v4.2.7 datasets include results from trio small variant, de novo structural variant and de novo copy number variant calls on 602 trio families comprised of members from the 1000 Genomes Project Phase 3 dataset. Trio repeat expansion calling was included in the v3.7.6 dataset only. Joint cohort analysis was also performed on the entire 1KGP sample dataset (n=3202) for the v3.7.6, v4.0.3, and v4.2.7 reanalyses using DRAGEN GVCF Genotyper v3.8.3, v4.2.0, and v4.2.7, respectively ([...]